Planting patterns through growth indices affect yield formation. To evaluate these effects on safflower, Koseh local variety of Isfahan, a field experiment was conducted in summer, 2004 at the Agricultural Research Station, Isfahan University of Technology. The experiment was performed using a randomized complete block design with a split plot layout and four replications. Main plots consisted of three row distances (20 and 30 cm flat and 45 cm on bed), and sub-plots included two planting densities (40 and 50 plant m^-2). The experiment was planted on June 25. The results showed that p lant canopy closed sooner, leaf area duration (LAD) increased and plant dry matter weight, leaf area index (LAI) and crop growth rate (CGR) were higher up to the middle of seed development as row distance decreased. In addition, the highest relative growth rate (RGR) and net assimilation rate (NAR) were obtained in 20 cm row distance. The highest (3039 kg ha^-1) and lowest (1930 kg ha^-1) seed yields were obtained with 20 and 40 cm row distances, respectively. Plant density did not affect the rate of canopy closure, CGR, RGR, NAR and seed yield. But, maximum plant dry weight, higher LAI and lower LAD values were obtained with 50 plants m^-2. The results obtained in this experiment indicate that 20 cm row distance with 50 plants m^-2 might be appropriate for summer planting of safflower, a local variety of Isfahan, under similar conditions.