Blast, caused by Magnaprthe grisea, is often an important fungal disease in the production of rice in temperate and tropical areas including Iran. To determine reaction of rice cultivars against blast disease, 40 rice genotypes from Iran and other sources from Asia were selected. Four blast isolates from different races were used to test all rice genotypes in different greenhouse tests. In blast nursery, experiments were conducted in a Randomized Complete Block Design (RCBD) with three replications. In different experiments inoculated plant materials were evaluated for Infected Neck Number(INN), Neck Lesion Size(NLS), Infection Type(IT), Diseased Leaf Area(DLA), Area Under the Disease Progress Curve(AUDPC), Lesion Number(LN), and Sporulating Region Diameter(SRD). Most of the Iranian traditional cultivars together with CO-39 and C104-PKT showed susceptible reaction for AUDPC, IT, INN and NLS. Performance of improved cultivars from Iran, IRRI and NILs (except C104-PKT) was resistant. Some cultivars including Fujiminori, Onda , Hassan saraii were moderatly susceptible to leaf blast in blast nursery. All components of resistance in both growing stages in greenhouse and nursery tests were significantly correlated. In some cases such as cultivar Haraz different reaction was observed in seedling and flowering stages, indicating that genetics of resistance in two stages could be different.